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Beilstein J. Org. Chem. 2015, 11, 875–883, doi:10.3762/bjoc.11.98
Graphical Abstract
Figure 1: Selected examples of biologically active thiazole containing molecules [12-20].
Scheme 1: Illustration of substrates that form thiophenes under Gewald-type conditions.
Figure 2: Substrates which did not react under the optimised conditions.
Scheme 2: Proposed mechanisms for the formation of thiazoles.